BDBM50353747 CHEMBL561013::JWH-018

SMILES CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12

InChI Key InChIKey=JDNLPKCAXICMBW-UHFFFAOYSA-N

Data  18 KI  1 IC50  2 Kd  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50353747   

TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]WIN-55,212-2 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataKd:  6.5nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes assessed as dissociation rate constant at 10 uM by liquid scintillation anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataKd:  3.40nMAssay Description:Displacement of [3H]JWH-018 from CB1R/CB2R in Wistar rat brain membranes assessed as dissociation constant by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1/2(Rattus norvegicus (Rat))
Biological Research Centre Of The Hungarian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50353747(CHEMBL561013 | JWH-018)
Affinity DataEC50:  36nMAssay Description:Agonist activity at CB1R/CB2R in Wistar rat brain membranes after 60 mins by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed